I had my DNA analyzed by 23AndMe and in addition to getting some somewhat innocuous reports on my genetic makeup (including the revelation that there is about .5% match each with Askenazi and African groups somewhere in my ancestry, plus some Neanderthal genes) my data has been anonymously included in nine published articles/studies so far, including:
- 23and Me blog article on Depression and genes: https://blog.23andme.com/23andme-research/new-genetic-findings-on-depression/ The original (abstract of) the article on genes associated with depression: http://www.nature.com/ng/journal/v48/n9/full/ng.3623.html
- On genes related to risks of basal cell carcinoma: https://blog.23andme.com/23andme-research/new-study-on-genetics-of-common-type-of-skin-cancer/ Original article in Nature Communications: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992160/
- AND OTHERS which can be found at 23AndMe Blog – Research category
Live long and Prosper!
A step towards more accurate diagnoses of Parkinson’s and other similar neurological diseases was recently reported in Nature. And by CNN which picked up the story: Parkinsons disease blood test study
Up until now, many diseases have been diagnosed based on symptoms, with patients asking, “How do you know I have this?” Meanwhile, doctors are not always correct, Wright said. This is true even of Parkinson’s, which is diagnosed based on symptoms, a patient’s history, neurological exams, a patient’s response to medicine and, in some cases, brain imaging tests.
As a person with Parkinson’s among other conditions, related or unrelated, this would be a big deal. When a diagnosis is based on having a specific array of symptoms, some of which might not be present in all cases (tremors, for instance), one wonders whether medications for reducing certain symptoms might not prevent the presentation of all the symptoms required for a diagnosis of Parkinson’s.
It does me little good to play “what if” since one doesn’t know how one would have reacted to an earlier diagnosis at an earlier age. One can only refer to Victor Frankl’s work on the search for meaning in our lives, and approach the present as though one has already been at this decision point and are being given a second chance to make a decision just as wrong as the original decision. At least that’s how I remember that particular quote. Here’s another quote from Frankl:
the meaning of life always changes, but that it never ceases to be. According to logotherapy, we can discover this meaning in life in three different
ways: (1) by creating a work or doing a deed; (2) by experiencing something or
encountering someone; and (3) by the attitude we take toward unavoidable
suffering. The first, the way of achievement or accomplishment, is quite obvious.